The basis of the pharmacological action is a modification of isoniazid molecules by complexation with iron. This provides the chemotherapy of tuberculosis, since the molecules of isonicotinic acid hydrazide chelate node blocked iron loses the ability to interact with the active sites of metal containing enzymes, including the primary amino hydrazine chelate cycle complex prevents interaction with the N-acetyltransferase.
Therefore boldenone acetate is low toxic drug in the application which does not require correction of single and course doses depending on its rate of acetylation.
Slowly absorbed, time to maximum drug concentration in the blood of 5-6 hours, the half-life is 7.2 hours.
Indicated for the treatment of patients with tuberculosis of different localization, including the related diseases of the central nervous system, liver and poor tolerability of isonicotinic acid hydrazide .
Hypersensitivity, pulmonary heart disease, coronary heart disease boldenone acetate, violation of blood clotting, thyroid dysfunction, pregnancy, lactation, children’s age.
DOSAGE AND ADMINISTRATION
The inside is 30-40 minutes. after meal. On the first day take 250 mg (1 tab.) In the morning (to clarify individual tolerance), etc., in the absence of adverse reactions, 250 mg in the morning and evening, for 6 months.
possible cardiotoxic effects, accelerating the processes of thrombosis, myocarditis, headache, diarrhea disorders, hypothyroidism, hemosiderosis parenchymal organs.
Symptoms: increased severity of adverse reactions. Treatment: removal of the drug, gastric lavage, symptomatic therapy. A specific antidote is not installed.
Interactions with other drugs
Because boldenone acetate (chelate kompdeks isoniazid and ferrous iron), the combined use of Fenazid ® and isoniazid is contraindicated.
During treatment requires systematic (not less than 1 time per month) monitoring ECG and coagulation.
Tablets 250 mg. 50 pieces in a polymeric jar or 10 tablets in blisters. Every bank or 5 contour cell package, along with instructions for use are placed in a pile of cardboard.