The most important risk factor for cervical cancer is persistent papilloma virus infection. There are reports of some increase in the risk of cervical cancer in long-term use of combined oral contraceptives.Communication with the reception of combined oral contraceptives has not been proved. Saved controversy as to the extent to which these findings are associated with screening for cervical abnormalities or with features of sexual behavior (a rare use of barrier methods of contraception).
It was also found that there is a slightly increased relative risk of developing breast cancer diagnosed in women who used combined oral contraceptives boldenone acetate gainsbourg. The increased risk disappears gradually within 10 years after discontinuation of these drugs. His connection with the intake of combined oral contraceptives has not been proved.
The observed increase in risk may also be due to an earlier diagnosis of breast cancer in women who use combined oral contraceptives. In women, ever use a combined oral contraceptives, revealed earlier stages of breast cancer than women who never they do not apply.
In rare cases during treatment with combined oral contraceptives was observed the development of liver tumors, which in some cases led to life-threatening intra-abdominal bleeding. In case of severe pain in the abdomen, liver enlargement or signs of intra-abdominal bleeding it should be considered in the differential diagnosis.
- other conditions
Women with hypertriglyceridemia (or in the presence of the state in family history) may increase the risk of developing pancreatitis while taking combined oral contraceptives.
Although a slight increase in blood pressure have been reported in many women taking boldenone acetate gainsbourg, clinically relevant increases were rare. However, if while taking combined oral contraceptives develops persistent, clinically significant increase in blood pressure, should be discontinued these drugs and begin treatment of hypertension. Acceptance of combined oral contraceptives may be continued if using antihypertensive treatment achieved normal blood pressure values.
The following conditions have been reported to develop or worsen both during pregnancy and while taking combined oral contraceptives, but their relationship with the intake of combined oral contraceptives It has not been proven: jaundice and / or pruritus related to cholestasis; the formation of gallstones; porphyria; systemic lupus erythematosus; hemolytic uremic syndrome; chorea; herpes gestationis; hearing loss associated with otosclerosis. Cases of Crohn’s disease and ulcerative colitis during treatment with combined oral contraceptives have also been described.
Acute or chronic disturbances of liver function may require the cancellation of combined oral contraceptives as long as liver function tests have not returned to normal. Recurrent cholestatic jaundice, which develops for the first time during pregnancy or previous use of sex hormones, requires discontinuation of combined oral contraceptives.
Although combined oral contraceptives may have an effect on insulin resistance and glucose tolerance, there is no need to change the therapeutic regimen in diabetics using boldenone acetate gainsbourg. However, women with diabetes should be carefully observed while taking combined oral contraceptives.
Sometimes it can develop chloasma, especially in women with a history of chloasma during pregnancy. Women with a tendency to chloasma while taking combined oral contraceptives should avoid prolonged exposure to sunlight and ultraviolet radiation. Laboratory tests using combined oral contraceptives can affect the results of certain lab tests, including liver function tests, kidney, thyroid gland, adrenal glands, the level of traffic plasma proteins, carbohydrate metabolism, coagulation and fibrinolytic parameters. Changes do not usually go beyond the normal range. The effect on the menstrual cycle While taking combined oral contraceptives may experience irregular bleeding (spotting or breakthrough bleeding), especially during the first months of use. Therefore, the evaluation of any irregular bleeding should be done only after a period of adaptation of approximately three cycles. If the irregular bleeding recur or occur after previous regular cycles, you should conduct a thorough examination to exclude malignancy or pregnancy. Some women during a break in taking pills can not develop withdrawal bleeding. If combined oral contraceptives are taken according to directions, it is unlikely that the woman is pregnant.Nevertheless, if before that combined oral contraceptives are taken irregularly or if there are no two consecutive withdrawal bleeding, to continue receiving the drug should be excluded pregnancy. Medical examinations or before boldenone acetate gainsbourg the resumption of the drug Femoden should be familiar with the history of life, a family history of women spend a thorough general medical (including blood pressure measurement, heart rate, body mass index) and gynecological examination (including breast examination and cytological examination of cervical mucus), exclude pregnancy. The amount of additional research and the frequency of check-ups is determined individually. Generally, control examinations should be carried out at least 1 time per year. It is necessary to warn the woman that type Femoden medications do not protect against boldenone acetate gainsbourg infection and other sexually transmitted diseases through! Effects on ability drive and technology.